AMSI is Ireland's National Member Organisation of the International Federation of Medical Student Associations (IFMSA) & represents Irish Medical Students On the 9th of November 2013, Medical Students from across the country came together for the inaugural National Medical Student Summit. This summit led to the launch and establishment of the Association of Medical Students, Ireland (AMSI). For the first time since the late 19th century, Irish medical students have an organisation that can facilitate dialogue at a national and international level.

The national organisation aims to:

- Increase collaboration between the medical schools
- Represent the views of medical students on a national scale
- Promote medical student health and well-being
- Create a forum where students can discuss a range of scientific and social topics
- Be a platform for Medical Students in Ireland to collaborate internationally with other Medical students.

AMSI is Ireland's National Member Organisation of the International Federation of Medical Student Associations (IFMSA) and represents Irish Medical Students' values and opinions at an international level through this forum.

IFMSA works on the local and national levels mainly via its six standing committees, each of them focusing focus on major health topics and medical student-related interests:

1. Public Health (SCOPH)
2. Sexual and Reproductive Health including HIV/AIDS (SCORA)
3. Medical Education (SCOME)

4. Human Rights & Peace (SCORP)
5. Professional Exchanges (SCOPE)
6. Research Exchanges (SCORE)

These abbreviations are used frequently in the organization. All start with SCO (Standing Committee on) and end with the abbreviation of the Standing Committee itself (PH – Public Health).

Each Standing Committee is headed by an International Director, who is supported by an international team generally consisting of one Liaison Officer (who is responsible for communication with relevant external partners) and five Regional Assistants (one from each of IFMSAs five regions). On the national level, the Standing Committee is coordinated by the National Officer, who is elected at each NMOs National General Assembly. On the local level the work is executed by one or more Local Officers