Timeline Photos

DNA takes as many as 160K hits a day. DNA damage can cause functional changes. The genotype doesn't change, however, as more genes become clearer there may be inclusion in reporting as research continues. The bigger question; How do I prevent negative transcriptions from outside influences which include the mobilome, exposome, bacteriome, virome, mutanome, etc to hit susceptibility in your genotype / phenotype? These influences can be addressed to a good degree! Minimizing DNA hits will assist in keeping functional longevity! Also, programming positive epigenetics back to the genome will also create healthier functional control. Genome susceptibility can be positively influenced by positive nurture and actionable changes!

Autism related genes - GeneCards Search Results

As research advances the number of genes implicated in autism increase! It is essential to know pathway implications and interpret these carefully as misdiagnosis can result from incomplete survey! Not all of these genes demonstrate high evidence or confidence and some are very strongly implicated. There are other factors to consider before jumping to a diagnosis conclusion. Some of these factors include thyroid disorder, adrenal insufficiency, glycemic disequilibrium, neurotransmission, choline metabolism and deficiency, high mitochondrial oxidative stress and calcium trafficking, which suppresses mitochondrial energy and alters protein transcription leaving proteins vulnerable to oxidative damage! The link lists implicated genes: http://www.genecards.org/Search/Keyword?queryString=Autism NFIL3, ITGA1, TCN2, TCOF1, FOXG1-AS1, FOXG1, ITGA6, LRP5, FOXE1, FOSB, TCF4, NIPBL-AS1, NIPSNAP1, IL2RA, FLT1, FMNL2, IL1RAPL2, IL17A, RPS27A, IFNG, HTR3A, IGFBP3, TBX1, IL12A, FHIT, LPXN, IKZF1, IL1RAPL1, TBX6, IKZF3, NGEF, NBPF3, NBPF2P, NBPF20, NBPF21P, NBPF25P, NBPF22P, GSTM1, FBXW7, NCKAP1, NAALADL2, GTF2I, GTF2IP1, NCOA3, IL2, IL5, ING3, INPP5D, TCF20, IQCE, IL1RN, IL2RB, FMR1, FMR1-AS1, TCF12, INPP1, NIF3L1, IPW, INCA1, IFNA1, HTR2C, TBC1D24, TAT, HTR2A, HTR7, HTR1A, HTT, IFFO1, HTR1B, FGF9, IGF1, NFIB, TBC1D7, TBL2, NFIA, HTR3B, IGFALS, NFKB1, FLG, HTR3C, FMR3, NHS, IL15, IMMP2L, NHSL1, FNDC3A, IKZF2, ITGB3, NKX2-6, JMJD1C, FOXP1, FOXL2, JAKMIP1, LRP4, NETO1, FGF8, HTR1D, HTR6, NF1, NIPA2, NIPBL, IPO13, LRP2, RYR2, NRG1, NTRK2, OPN1LW, POMC, NRAS, NTF3, NSUN5P2, NUP62, OAT, SCARF2, OMG, OR10A7, NTRK3, OCA2, NTNG2, NRXN1, NRXN2, NTS, OCRL, PPP2R5C, PHF21A, PIH1D2, SDHC, PQBP1, ASTN2, MIF, MIPOL1, MGAT5B, MECP2, MEF2C, NRXN3, NUP54, NTRK1, ARNT2, NSD1, NTF4, SCAMP5, MAPK3, POM121L7, NSUN5, NSUN5P1, PPIG, SCT, PDLIM7, PDE4D, PPP1R1B, ASIC2, PENK, SCTR, PDE4DIP, PEX7, PDE4B, PDXK, PEX12, TMEM100, PDZK1, PDE4A, PDP1, PPP1R12A, PDYN, PRKAA1, PRODH, PRICKLE2, PIK3CA, ATF6, PRRG4, PRDM16, PRICKLE1, PRD, SDC2, PPP2R4, ASPG1, ASPG3, ASPA, PI4KA, PHF8, ASMTL, ASMT, PPP1R3F, PER2, PER1, PIAS2, SDCBP, PDS5A, SDHB, PEG13, PECAM1, PIK3R2, SDHD, PIK3CG, TMEM185A, PRDM14, PIGL, PRKAA2, PPP4C, PSTPIP1, PRLR, PSS, RTL1, LOC101930332, TGM1, TGFB3, LOC101928890, LYPD1, THBS1, MAGED1, NPY, RYR3, MAG, S100B, MAGEA11, NPY1R, MAGEL2, NPY2R, MAGEA8, POGZ, NPTX2, MBD6, MAP2, MBIP, SALL1, MAZ, NR1H4, SALL4, MBD4, POLG, MAPK8IP2, MBP, MBS3, MCF2, MBS1, MBS2, MBD5, MAU2, MCPH1, TGFA, TG, NPAS2, GAS1, GATA1, NPAS3, GATM, ARHGAP24, ARID1B, NR2E1, MED4, MC3R, MCM7, MED12, MDFI, MDGA2, MC4R, MBD2, MCHR1, MBD1, MAGEA4, NPY5R, MARCH10, NR1D1, MAOA, MARK1, MAP1B, NQO2, THPO, MAPT, LZTS2, TH, PLXNA3, MAB21L1, PLXNA4, TGFB1, NPAP1, GATAD2B, MAGEA2B, MACROD2, MAOB, NLGN4Y, JADE1, ITGA3, ITGAV, NLGN3, TDRD3, KATNAL2, RPS6KA2, ITSN2, NLGN4X, FRA16A, FOXP2, NLGN2, NLGN1, GABRG1, KLLN, NOL4, KPNA3, NOL4L, GABRB3, NOTCH1, PNOC, NOSTRIN, NOTCH2NL, GAMT, PLD5, KCNJ11, FRAS1, NLRP3, KCNAB2, APP, FSD2, APPL2, KCNQ3, KCNN3, KCTD9, PLSCR1, GABRQ, GABRA2, GABBR2, KRT12, KRT10, TF, GABBR1, GABRR1, GABRA4, NOS1, GABRA3, GABRG3, KPTN, GABRA5, KNG1, KCNJ2, KANK2, RPS6KA6, FRAXE, JUP, KCNE1, KCNK9, KCNH5, ITGA4, KANTR, FOXO1, APOE, KCND2, PLXND1, KMT2A, LRRTM3, G6PD, FZD9, NODAL, GABRA1, KMT2D, GABRG2, LRRN3, LRRTM1, LRRN1, KIAA0319, KDR, KDM4C, NMNAT1, FTH1, KDM5C, GAD1, NOS2, GABRB2, TFCP2, GAD2, GABRB1, GABRD, GALNT13, TFPI, NOVA2, TFIP11, TFP1, RELN, SETBP1, SHANK3, SLC1A2, TSC2, TSPO, TSC22D4, TUB, TTR, UBASH3B, TUBB3, TTC23L, TWIST1, UBE3A, UBE2QL1, UBE2H, TUBGCP4, SH2B1, TNKS, TPH2, TPH1, TOR3A, TPMT, TOX4, TP53BP2, TRAF1, SLC25A1, SLC15A4, SLC19A1, SIM1, SLC1A1, SLC30A4, SLC35A3, SHOX2, SKI, SERTAD1, SLC13A1, TRAF4, TNS2, TRIM37, TSPAN12, TSSK1B, TSPAN7, TSC1, TTC1, TSSK2, TRIP13, TRMU, TRIM23, TRIM73, TRIM74, SLC11A2, SLC25A12, SLC25A14, SLC25A13, RASGRP1, SKIL, SLC12A6, SLC1A3, TYR, VCX3A, UGT1A1, USP15, USHBP1, ATP2B2, UPF3B, TYMS, ATP2C2, UFD1L, UBQLN1, UPP2, UBXN11, UBL5, TRIM32, TRDN, TRIM42, TRIM54, TRIM50, TRIP6, TRAF6, TRAF2, TRIM27, TRIM10, TP53, TRIM33, U2AF1, TXLNA, TXLNB, TPO, SEPT5, SEPT2, RAPGEF4, QDPR, PTCHD1, PTK2, RAD9A, ATP10A, RAC1, RBCK1, SEPT6, SEPT9, RAP1GDS1, PRKCA, PRAP1, PRPF40A, PRPF40B, PROK2, PTCH1, PTPRZ1, PTPN3, SELP, PTS, PRRT2, PSEN1, PRKAG1, PTGIR, PRKCB, PXDN, PTGS2, RAB39B, PYY, PTPRA, PVALB, PYGM, PTLS, PTEN, TMEM79, SEMA5A, SEPT1, RABGEF1, RAB3A, RAB3IP, TMLHE, PSMA3, RAD21, RAD23A, QPRT, RAB11FIP5, REEP3, SETDB1, SHANK2, PSMD10, SHANK1, SHH, SHMT1, PSMC2, SEMA3E, PTCHD1-AS, PWAR5, PWARSN, PWRN1, TNF, SHARPIN, SEZ6L2, REG3G, SGCE, SERPINA1, REG1B, REG1A, RBPMS, PSME3, RASSF5, RASSF7, RAI2, RAI1, SERTAD3, SETD5, RCBTB2, RCHY1, RBFOX1, REL, PROKR2, PRKAB2, PRR20A, PRL, PROP1, SCN3A, PCBD1, OPRM1, NRIP1, ARSC2, ASAP2, PAPPA, PAX6, PCDHA12, PAFAH1B1, SCN4B, MET, MDM2, MICU2, MEST, MID1, MINPP1, MEIS2, MEOX2, MFSD6, MED15, OPRD1, OPRK1, SCG5, OPRL1, OR6C76, OR6C75, OR6C1, OR6C3, ARSH, OR6C2, OR6C68, POU1F1, OTX1, TLR4, OSBPL6, P4HA3, OR6C74, OR6C4, OR6C64P, OR6C6, OR6C65, OTUD7A, OR9K2, PPFIA1, ARVCF, OTX2, ARX, PAH, SCN1A, TM4SF20, SCN2A, OXTR, PAX2, OXT, SCN8A, PCDH9, PARD3B, PCDH19, PCDHA@, PDLIM1, PCDH10, PARK2, NUBPL, OR10P1, OPHN1, NRP2, PON1, ARNTL, ARNTL2, OBFC1, SATB2, SAXO1, NRCAM, TIMP4, MICE, MIER2, MEOX1, MID2, MIR137, OR6C70, NTNG1, POU6F2, KIF1A, KIF7, KIF1BP, FUNDC1, KIAA2022, AQP4, TDO2, FRAXA, KCNJ10, FKBP6, TBL1Y, NFXL1, FIGNL1, IL18R1, IL10, NGF, KLF15, TERT, FZD4, NOBOX, FXR1, KLF13, KLF3, KLF7, KIFC3, FXYD1, FXN, KLF12, PLN, AR, FXR2, FGFR1, HTR5A, PLEKHG3, KCNMA1, KCNQ1, IL1B, KLHL12, VCP, ZNF398, ZNF407, ZNF778, ZNF74, XRCC5, ZBTB18, ZBTB1, XIRP2, ZEB2, VEGFA, XG, ZC3H11A, AUTS8, ZNF713, ZNF804A, ZNF711, GPR155, MVP, FABP7, AP1S1, SSX2IP, GPR89B, GPR89A, GPRASP2, GPR85, GPRC6A, SSBP3, EXT1, EXT2, GOLGA2, SRY, STATH, LMO2, APC, FAM131C, APBB1IP, AKR7A2, GH1, GHR, SOX10, SP1, GJA5, GJA8, RNF31, GJA1, AKT1, GDF1, GHRL, EPHA3, MRPL19, RNF166, GHSR, SOX9, GDI1, SORBS3, GDNF, MRE11A, SOD3, GET4, AHI1, SOD1, GFAP, SOD2, SMC1A, SMC3, LEPR, MME, LHFPL3, ADA, LIMK1, SNAP23, ELP4, SMTNL2, ELN, RNASET2, AGTRAP, EP300, MPP2, AGRP, MRPL40, SOX14, RNF111, SOX2, RNF213, SP4, SPAG16, SPAG5, SPAG8, AKT3, MRXSL, SPDYE1, MT-ND4, AMPD1, SRCAP, MT-TF, MT-TH, MT-TL1, MT-TK, MT-ND5, ESR2, GNAQ, AMELX, ALX4, AMOT, MTRR, ERBB4, GLRA2, ALMS1, ALMS1P, MT-CO2, ERC1, MT-CO3, MTERF1, MTNR1A, MTNR1B, MTOR, GNB1L, MTR, SPECC1L, ERBB2, ALDH5A1, ALDOA, MT1A, ALDH3A1, GLO1, MT-ATP6, SPR, ALG13, MTHFR, ESCO2, SPRY2, MT-ND1, MTMR12, ALX3, GKAP1, ALDH3A2, SPERT, ALDH1B1, GLUD2, MTHFD1, MTF1, MT-CO1, MTMR10, ALPP, GNPTG, EXOSC8, ANKRD11, ANK3, MT-TC, MT-ND6, MTO1, GRN, FASTK, FAN1, NBEA, FBN1, NBPF15, NBPF17P, SWAP70, NBPF18P, NBPF4, NBPF6, NBPF7, NBPF12, NBPF14, NBPF10, NBPF13P, NBPF1, FBN2, HLA-DRB1, NECAB2, HMGB1, FGF10, HDAC1, HDAC8, HFM, HMGCS2, NEFL, HLA-A, HLA-B, HLA-C, TAOK2, HOMEZ, HNF1B, HOOK2, TAS2R1, RPP25, TARDBP, HOXD@, HNRNPK, HOMER1, HOXA2, HOXD13, HOXA1, HOXB@, HOXB1, HOXD12, HOXD11, NDUFS4, HDC, HGF, TAF1C, NDUFV1, HES6, HGS, HIRIP3, HIF1A, HIRA, HRAS, HSFY1, HRH2, HDAC4, HELLS, HERC2, HESX1, HFE, HDAC2, HCRT, HCRTR1, HES1, HEPACAM, TADA2A, FGD1, RPL7A, NEBL, HLA-DRB3, TAF6, HMBS, NEDD1, HLA-DRB4, HIST4H4, HMGCR, HTN3, HTR1E, NEUROG1, FGFR3, NEU2, HRH1, HTN1, GP9, MUC1, GOPC, SS18L1, GPC1, MT-TW, ANOS1, MT-TS1, MT-TS2, MTUS2, ROBO2, ROBO4, STK11, GREM1, STK39, MYO1D, FAM168A, GRIA1, GRIA2, RPA1, RP1L1, STK38, GREM2, GPHN, FA2H, ST8SIA2, ST7-OT3, GPHA2, ST7, FABP5, GPM6B, MT-TQ, ANPEP, FABP3, GP1BA, GP1BB, SST, SSTR5, AP2B1, STAG3, MYC, APBA2, GPR50, FAM124B, FAM120C, GRIN2B, N6AMT2, GRIN2D, MYT1L, NAB2, GRIA3, STRADA, RPIA, RPGRIP1, RPGR, RPL10, MYH9, LMX1B, LNX1, ROBO3, GPX1, GRIP1, NAGA, FAM9B, GRIN2C, ABCA13, DYX1C1, ABCA1, ABCB1, LASP1, ACE, LAX1, SLC8A2, ACHE, LAT2, EHMT1, MKL1, MKL2, SLC9A6, LBX2, ACP6, SLC9A9, ACP1, RHOXF2, LCORL, RIMS3, SLITRK1, SLITRK2, MLPH, RINT1, MLXIPL, LCOR, ACTA1, LDOC1, EIF4E, EIF4EBP1, SMAD4, LDLRAD3, EIF4ENIF1, EIF4EBP2, RIPPLY3, LDLRAD1, RIMBP3, ACSL4, EIF2B5, MLC1, MKRN2, MKRN3, EIF1AY, EID1, LARS2, EGR2, SLC6A8, SLC7A4, LARGE, RHEBL1, SLC7A7, SLC7A5, RGS20, EIF4EBP3, EIF4H, LEP, SMARCA5, LGI1, LHX3, LIFR, LEPQTL1, SMO, LHX1, SNRPN, AGMO, SNTG2, GCH1, SNURF, GCHFR, ADIPQTL3, ADORA3, LINC00969, ADH4, ADH7, ADHD1, ADH1B, ADH6, ADM, ADNP, ADORA2A, AES, AFP, AGAP1, AFF2, ADSL, SND1, LIN7B, EMP2, MOG, EN2, SNORD123, SNORD116-11, ADCY9, ENKD1, ADAMTSL4, ADCYAP1, ADH5, ADH1C, ADH1A, SNORD64, ADIPOQ, GCC1, NAGPA, GRM1, NAPB, FARP2, GRM8, PITX3, PITX1, FARS2, PKMP1, GRM7, GSTT1, FBXL4, NCAM1, SYN1, GSTP1, SYNGAP1, SYN2, GSX1, H2AFY, GTF2IRD2B, GTSCR1, FDFT1, NDP, NDEL1, GTS, NDUFA5, TAC1, HADHA, TACC3, HBA1, HBA2, HCCS, HBB, FEZF1, GUSBP5, HDLBP, SUMO1P1, SUMF1, GRM5, NBPF8, SYCE1, NBPF9, SYCE3, GSTM3, GSC, FBF1, GSC2, GRPR, GSE1, GTF2IRD1, NDC80, NDE1, GTPBP3, NDNL2, NDN, GZMB, GTF2IRD2, HAGH, HCRTR2, RETN, REV3L, RFC1, RFC2, SLC4A10, LAMB4, EFEMP2, LAMB1, SLC4A11, SLC4A4, RFWD2, EFHC2, EDA, L1CAM, EEF1A1, ABHD11, RET, DYRK1A, DYM, DYDC1, AANAT, ABAT, ACADL, RFX4, RFX6, SLC6A14, EFS, SLC6A2, ACADM, SLC6A1, ACADSB, L3MBTL3, ABHD11-AS1, SLC4A5, SLC40A1, EGF, SLC6A3, SLC6A4, STAG2, GPR37, APAF1, ROBO1, GPRIN3, RORA, GRIK2, STS, MYOG, GRIN2A, STOML1, FAM208B, GRIN1, STX11, STX1A, STX19, FAM46C, STXBP1, ADCY1, SNORD115-37, ADRA1A, ADRA1B, ADRA2A, ADGRA2, SNORD115-38, MMP9, SNAP29, SNAP25, LINC01162, ADRB2, CBS, CASP3, CCDC136, BCL2, CARS, BRCA2, CARS2, CALB2, CAMK4, BRCA1, CARD9, CACNB2, CALCA, CAT, WBSCR28, WBSCR27, VIPR2, VIP, WBSCR22, VPS13B, VAC14, WBS2, VWA8, VPS52, WBSCR2, VLDLR, CCK, CDC23, CALCOCO2, CBLL1, CASP9, CCL17, CCND2, CDCA7L, CAMK2B, XDH, WAC, WT1, WFS1, WNT2, YWHAB, ZBTB7B, ZC4H2, XPO1, ZBTB32, YWHAZ, BTBD9, CADPS2, CA6, CASK, CADM1, CARTPT, CALB1, C9orf16, CA3, ATRX, CABLES1, C4B, BDNF, BTD, BMPR1A, C16orf72, BZRAP1, C16orf45, C1orf94, BICC1, BGLAP, BMIQ16, BAIAP2, BAZ1B, AUTS12, AVPR1B, BHLHE40, BEND5, BCAS2, BCKDHA, BLZF1, AUTS6, CCDC57, CACNA1C, CCDC148, CCND1, CCL2, CAMK2A, CACNA1G, CCDC36, CCDC33, CCDC67, CCDC102B, WBSCR16, UGT1A6, WBSCR17, VPS37D, VAMP7, VAMP5, XPC, ATP6V0C, WNK3, ZBED1, ZFYVE21, ZNF365, ZMYM3, ZNF341, ZMIZ2, ZDHHC8, ZFR, ZMYM2, CHAT, CDX4, CLDN4, CHN1, CHRD, CLIP2, CHURC1, CLTCL1, CMIP, CLCN2, CMTM5, CHRM5, CGGBP1, CHGA, CER1, CLDN3, COPS2, CNTN4, CMC1, CMAHP, COL11A1, CNC2, CHRNA4, CECR5, CDR2, CECR6, CEP76, CPA1, CRADD, CSRNP3, CRMP1, CPOX, CNTN6, CRKL, CNTNAP1, CSDE1, CYP11A1, CYP21A2, D2HGDH, CTNNA2, CYFIP2, CTNND2, CTNND1, CUX2, CYFIP1, CYP11B1, CTBP2, CTHM, COMT, CUEDC2, CIB2, CDH10, CDH8, CDH15, CDK14, CDH9, CECR9, CHRNB2, CDX2, CEP57L1, CEP44, CLDN5, CHDS3, CECR2, CD69, CCL26, AUTS13, BCL7B, AVP, AUTS1, AUTS11, AUTS2, AUTS3, BANP, AUTS5, AVPR1A, AUTS7, BTN1A1, BCKDK, BLOC1S6, BST1, ZBTB20, ZNF385B, ZNF214, ZNF277, ZNF446, CACNA1H, C9orf72, C4A, C3orf58, C3orf62, CACNA2D1, CD40LG, CECR1, CAMK2G, CDKN3, CDL1, CDL2, CNTNAP2, CTU2, CTCF, CREB1, CSNK1E, CREBBP, CPA2, CP, CRX, CTTNBP2, CTBP1, CTAGE5, CTNNA3, DAO, DAOA, DELXP22.11, DAND5, CSMD3, DEPDC5, CSN1S1, DDX21, DCUN1D1, DUP1Q21, DUP22Q11.2, DLG4, DPYSL2, DNPEP, DNAJC30, DLG3, CHD8, CHD1L, CEP63, CEP68, CEP126, CEP70, CD79A, CDKL5, CDH13, CDH7, CHD7, CEP41, CDH12, CNR1, CHRNA7, CHRNA6, COL5A1, CNTNAP5, COPG2, CNR2, CREB3L1, CPLX1, COBL, CPA5, CTSC, CTNNB1, CUX1, CXorf36, DAB1, DAZAP2, DCX, DCTN1, DBH, DEL17Q12, DEL2P16.1-P15, DDX53, CD38, DDC, DEL1P36, DCP1A, DGCR8, DENND2C, DISC1, DLGAP2, DLX1, CELF6, DLX2, DHFR, DHCR7, DLX6, DHPS, DIO3, DICER1, DLX3, DEL3Q13.31, DEL15Q11.2, DEL15Q13.3, DEL4Q21, DEL16P11.2, DPY30, DUPXP11.23P11.22, DUP7Q11.23, DUP16P11.2, DPP6, DOCK4, DTX2, DPYD, DOCK3, DOC2A, DOCK8, DRD2, DPYS, DPP4, CYP1A2, DLG2, DMPK, CYP2D6, DLX5, DGCR, DGS2, DGCR2, DGCR6, DGCR6L, DGCR14, DRD1, DPP10, DTNBP1, DUP17Q21.31, DRD4, DUSP13, DRD3, DUSP19, DRP2, DRD5, DRG1

Interested in Courtagen Genetic testing? Read My Tips! - BioMed Heals

http://www.biomedheals.com/2016/02/interested-in-the-courtagen-genetic-testing-here-are-some-helpful-tips.html

Courtagen | Genetic Testing

From Julie Horney For those following my case, I am pleased to be adding this sophisticated testing under the care and direction of Dr. John Catanzaro. Use of other genetic testing such as that from www.23andme.com was inconclusive. We are hopeful again! www.courtagen.com

Timeline Photos

How Healthy Is My Genetics? A very common question I am asked! A better question is how damaged is my DNA? DNA Damage DNA is the architectural matrix of genetic information in each living cell, so its integrity and stability is essential to functional health. DNA is constantly being damaged by environmental factors like exposure to ionizing radiation, ultraviolet light and toxins. DNA replication is also prone to error during normal cell division, so your body is busy constantly repairing damaged DNA. However, sometimes this normal DNA repair process fails, causing damage and genetic mutations to accumulate which leads to serious health problems like cancer, immunological disorders and neurological disorders. Knowing Not Guessing! Assessing DNA damage, knowing your genotype and phenotype expressions are all essential to mapping a better health action plan. It is crucial to know that just trying to address health conditions like leaky gut syndrome, chronic fatigue, chronic allergies, chronic infections without knowing your foundational map of DNA and genetic architecture can be both misleading, expensive, frustrating, incomplete and a long list of supplement and dietary restrictions that can be just as damaging as any bad drug! Don't Fly Blind HealthCoach7 www.healthcoach7.com and Courtagen Life Sciences www.courtagen.com, can assist you in knowing and not flying blind!

Low Dose Allergy (LDA) Therapy - Integrative Medicine Center

I have practiced LDA / LDI for 18 years successfully in autoimmune disease. Here is a good review of the process and protocol. It is expensive therapy and not covered by insurance! http://imcwc.com/html5-blank/low-dose-allergy-lda-therapy/

Services - Health Coach 7

DNA Testing and Adaptive Shifts How does this effect my health? 23andMe Genotyping Current advances in genetic science allows us to have our genome data. 23andMe profiles the genotype by giving almost 1 million single nucleotide polymorphisms on specific genes. This type of analysis is not the same as NextGen (next generation sequencing), which sequences the all genes and the entire genome. This genotyping is highly useful in demonstrating patterns of certain genes and their methylation, which may have some variation on functional health but do not cause full functional disease. Therefore this analysis cannot be used reliably to diagnose functional disease. The strength of genotyping is in revealing certain variations and when interpreted correctly will reveal some vital clues relating to functional health. Courtagen and Next Gen Sequencing Courtagen Life Sciences uses next generation whole gene sequencing technology. This analysis can be used to diagnose functional disease and reveal the degree of functional disease risk seen in inheritance patterns. It profiles both the nuclear and mitochondrial human genomes. This form of sequencing is a necessary process to reveal a clearer association of gene phenotype expression that contributes to the risk of expressed functional change and disease. Both Forms Are Needed! In my opinion, both 23andMe and Courtagen data are necessary when accumulating all available gene data in giving a better assessment and action based plan to reveal, minimize and improve functional health and minimize risk. This can greatly help physicians in helping patients recover from crippling symptoms of debilitating diseases and syndromes. HealthCoach7 / Clearer Guidance HealthCoach7 focuses in on providing clearer guidance for both doctors and patients, in revealing the relationships and correlation between 23andMe and Courtagen (Next Gen sequencing) profiles and their associated functional health and disease implications. Furthermore, Healthcoach7, gives both interpretation and functional guidelines to assist in developing a better clinical action plan. What Genes and SNPs Reveal? We speak of SNPs (Single Nucleotide Polymorphisms), also known as an insertion of a supposed, out of order sequence of a base pair letter. These shifts are commonly called mutations, however, I do not consider them to be rightfully called this, thus I use the term "adaptive shifts." These events are usually harmless, not of any major clinical significance and cannot be used as criteria to diagnose functional disease. However, there may be indications that certain SNPs on a specified gene expose the gene to a higher percentage of risk causing an epigenetic shift to harmful mutations. However, I firmly caution that SNPs alone in assessment can be misleading, you need both forms of data. The Gene is the "Boss"! My saying here is true. When it comes to revealing functional patterns that have impact on certain pathways in the body the gene is the boss. Genes make proteins that have functional action and they do impact health. Healthy genes, healthy people! How to have and keep healthy genes? Protecting DNA! Firmly, protecting healthy DNA of cells is the secret to preventing epigenetic shifts that are unfavorable. Vulnerable DNA causes epigenetic stress and is the culprit leading to unfavorable mutations and initiating oncogene activation and expression. Simply, vulnerable DNA is DNA that has been hit by an adverse force, exposure, cell environment stress and / or process of aging and chronic inflammation is often seen as a major contributor of DNA damage. Vulnerable DNA can be evident at birth of a new cell line. In other words, cell progeny can have vulnerable or damaged DNA from the start. Often, these cells that express damaged DNA are labeled with antigens that demonstrate movement toward altered cell expressions that can initiate disease and premature aging. Cells that have vulnerable or damaged DNA are prime to cause cancerous mutations if permitted to continue thrive, replicate and expand. We know this to be found in bad cells that flood the body and attach themselves in places they don't belong causing tumors and tumor formation or flat out destroying other healthy cells of the body. Cells need protection from excessive oxidative damage caused by environmental risk and inflammatory excess. Cell Protection Basics! When a cell is exposed to harm, vital components of the cell including the nucleus, mitochondria, endoplasmic reticulum, golgi and cell membrane are stressed. The nucleus is the command center, the mitochondria is the power house, the endoplasmic reticulum is the factory for protein manufacturing directed by the nucleus and powered by the mitochondria, the golgi is the shipping and distribution center. DNA is the foundation of it all. Damaged DNA!, Damaged Cell!, Damaged Proteins!, Damaged Shipping and Distribution!, No Protection!, Faulty and Disastrous Function! Damaged Offspring! I'm sure you get the picture. Genetic Data is a Blessing! As mentioned above, there are some very basic ways to protect. The wisdom of genetics is in applying knowledge directly, as it relates to functional health and getting results. Knowing personalized genetics is the starting place, the wisdom of personalized genetics is in its direct application. Otherwise, it's just another stream of useless data with no actionable value! Protect your healthy DNA! Minimize harmful exposures, be sure to nurture the body with protective foods and nutrients, encourage healthy biochemistry, minimize unhealthy progressive aging by identifying key inherent gene sensitivities and vulnerabilities, thus the value of 23andMe, Courtagen and HealthCoach7 implementation of translating genetics in terms of actionable functional health. These are powerful tools to influence your epigenetics in a powerful effective strategy for healthy longevity! https://www.healthcoach7.com/contact/

Dr. John Catanzaro

Some review on CBS gene!

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Dr. John Catanzaro

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